Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare diseases. Our most valuable resource is our employees, and everything we do is motivated by a patients-first mentality. We are dedicated to growing our team with talented individuals from around the world who are willing to challenge the status quo, solve problems, and work collaboratively with a sense of urgency and compassion.

Guided by our core values of collaboration, accountability, passion, respect, and integrity, we aim to foster an inclusive, diverse, and flexible work environment, where our employees are recognized for leaning in and rolling up their sleeves. If you share our vision and want to work with the most dedicated people in the biopharma industry, come to Insmed to accelerate your career.

We are looking for an innovative Cheminformatician with a background in computational chemistry who is passionate about the transformative power of data engineering, modeling, and ML/AI in drug discovery. In this role, you will work closely with our team of chemists, computational chemists, and data scientists, playing a critical part in developing Insmed Innovation's discovery design platform. This platform will leverage cutting-edge tools, data-driven methodologies, and machine learning to accelerate our drug discovery efforts. An exciting aspect of this position is the opportunity to collaborate with our AI group, implement and explore new methods and technologies that will revolutionize and enhance our drug design capabilities. This role offers an exciting opportunity to join and build a new team and be at the forefront of integrating advanced technologies into drug discovery, leveraging your expertise to make a tangible impact.

The role will focus on deploying, developing, and integrating cutting-edge tools, managing bioactivity databases, generating machine learning models, and collaborating with our broader data science and informatics team. Your work will enable broad access to these tools via APIs, supporting our designers on therapeutic development projects across various modalities from small molecules to more novel ones like oligonucleotides. By applying a broad set of computational chemistry and cheminformatics approaches, you will play a crucial role in advancing data-driven molecular design and medicinal chemistry efforts. Your contributions will have a significant impact across our global team. You will be responsible for, among other things:

• Deploying cheminformatics tools, workflows, and models to extract, integrate, analyze, and visualize complex chemical, structural, pharmacological, and ADMET data within the context of structure-based drug discovery.
• Playing an active role in assessing and deploying new computational chemistry tools through external collaborations.
• Exploring the application of AI-driven molecular design and generative approaches, including active learning.
• Curating and preparing datasets—including chemical data warehouses and data marts—to enable better data access, analysis, and modeling across our team.
• Engaging with technologies for data mining and virtual screening of ultra-large databases.
• Working closely with cross-functional teams, including biology, pharmacology, and ADME, to help identify opportunities for building datasets and models that will impact ongoing projects.
• Exploring new modalities, including using cheminformatics to help describe oligonucleotide chemical space to enable rational discovery.
• Identifying opportunities to publish in peer-reviewed journals to communicate any new insights, methods, or results to the scientific community.

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We’re committed to investing in every team member’s total well-being, now and in the future. We offer a competitive total-rewards package to all employees around the world, including:

• Competitive compensation package including bonus 
• Stock options and RSU awards
• Employee Stock Purchase Plan (ESPP)
• Generous paid holiday schedule and winter break 

Insmed Incorporated is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, disability, age, sexual orientation, gender identity, national origin, veteran status, or genetic information or any other characteristic protected by law.

Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application or interview process, please contact us by email at TotalRewards@insmed.com and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.

Applications are accepted for 5 calendar days from the date posted or until the position is filled.